1.
AIDS - First case in Congo (1959)
2. H1N1 (Swine Flu) - First case in Mexico (2009)
3. COVID-19 - First case in China (2019)
4. Ebola - First case in South Sudan (1976)
5. Bird Flu (H5N1) - First case in Hong Kong (1997)
6. Dengue Fever - First case in Manila, Philippines (1950s)
7. SARS - First case in Guangdong, China (2002)
8. MERS - First case in Saudi Arabia (2012)
9. Zika Virus - First case in Uganda (1947)
10. Spanish Flu - First case in USA (1918, believed)
11. Cholera - First case in Indian Subcontinent (Early 19th century)
12. Plague (Black Death) - First case in Central Asia (1347-1351)
13. Smallpox - First case in Northeast Africa (3rd century BCE)
14. Tuberculosis - First case in Egypt (3000 BC)
15. Malaria - First case in Africa (Prehistoric)
16. Yellow Fever - First case in West Africa (17th century)
17. Polio - First case in Egypt (1580 BCE)
18. Measles - First case in Middle East (7th century AD)
19. Typhoid Fever - First case in Ancient Greece (430-426 BCE)
20. Leprosy - First case in India (2000 BCE)
21. Syphilis - First case in Europe (1494)
22. Bubonic Plague - First case in China (1334)
23. Scarlet Fever - First case in England (1675)
24. West Nile Virus - First case in Uganda (1937)
25. Anthrax - First case in Egypt (1250 BCE)
26. Rabies - First case in Babylonia (2300 BCE)
27. Cholera - First case in India (1817)
28. Marburg Virus - First case in Germany (1967)
29. Mumps - First case in Ancient Greece (5th century BCE)
30. Rubella - First case in Germany (1814)
31. Lyme Disease - First case in USA (1975)
32. Legionnaires' Disease - First case in USA (1976)
33. Lassa Fever - First case in Nigeria (1969)
34. Hantavirus - First case in Korea (1950s)
35. Chikungunya - First case in Tanzania (1952)
36. Hepatitis B - First case in China (4th millennium BCE)
37. Hepatitis C - First case in Egypt (1940s)
38. Hepatitis A - First case in USA (1970s)
39. Q Fever - First case in Australia (1935)
40. Rickettsia - First case in USA (1909)
41. Mad Cow Disease (BSE) - First case in UK (1986)
42. CJD (Creutzfeldt-Jakob Disease) - First case in UK (1920s)
43. Rocky Mountain Spotted Fever - First case in USA (1896)
44. Nipah Virus - First case in Malaysia (1998)
45. Yaws - First case in Africa (Prehistoric)
46. Onchocerciasis (River Blindness) - First case in Africa (1893)
47. Trachoma - First case in Egypt (27th century BCE)
48. Dracunculiasis (Guinea Worm Disease) - First case in Ancient Egypt (1500
BCE)
49. Lymphatic Filariasis - First case in Egypt (2000 BCE)
50. Kala-azar (Visceral Leishmaniasis) - First case in India (1824)
51. Trichinosis - First case in Ancient Greece (1200 BCE)
52. Cysticercosis - First case in Mexico (1500 BCE)
53. Schistosomiasis - First case in Ancient Egypt (1900 BCE)
54. Tetanus - First case in Ancient Egypt (5th century BCE)
55. Diphtheria - First case in Ancient Egypt (5th century BCE)
56. Pertussis (Whooping Cough) - First case in France (1578)
57. Influenza - First case in Russia (1889)
58. Pneumonia - First case in Ancient Greece (4th century BCE)
59. Typhus - First case in Spain (1489)
60. Psittacosis (Parrot Fever) - First case in Switzerland (1879)
61. Scabies - First case in Italy (1687)
62. Trench Fever - First case in Europe (1915)
63. Yellow Nail Syndrome - First case in USA (1964)
64. Echinococcosis (Hydatid Disease) - First case in Iceland (1771)
65. Brugia malayi - First case in Malaysia (1927)
66. Alkhurma Hemorrhagic Fever - First case in Saudi Arabia (1994)
67. Crimean-Congo Hemorrhagic Fever - First case in Crimea (1944)
68. Rift Valley Fever - First case in Kenya (1931)
69. Chagas Disease - First case in Brazil (1909)
70. Sleeping Sickness (African Trypanosomiasis) - First case in Uganda (1901)
71. Leishmaniasis - First case in India (1824)
72. Leptospirosis - First case in Germany (1916)
73. Monkeypox - First case in Congo (1970)
74. Acanthamoeba keratitis - First case in USA (1973)
75. Babesiosis - First case in USA (1969)
76. Melioidosis - First case in Myanmar (1912)
77. Strongyloidiasis - First case in Italy (1876)
78. Scrub Typhus - First case in Japan (1899)
79. Tsutsugamushi Disease - First case in Japan (1899)
80. Eosinophilic meningitis - First case in USA (1945)
81. Histoplasmosis - First case in USA (1906)
82. Blastomycosis - First case in USA (1894)
83. Coccidioidomycosis - First case in USA (1892)
84. Paracoccidioidomycosis - First case in Brazil (1908)
85. Sporotrichosis - First case in USA (1898)
86. Cryptococcosis - First case in Italy (1894)
87. Mycetoma - First case in Venezuela (1842)
88. Penicilliosis - First case in USA (1956)
89. Aspergillosis - First case in Germany (1856)
90. Histoplasmosis - First case in USA (1906)
91. Listeriosis - First case in USA (1924)
92. Erysipelas - First case in Ancient Greece (11th century)
93. Amoebiasis - First case in Russia (1875)
94. Fascioliasis - First case in Russia (1883)
95. Gnathostomiasis - First case in Thailand (1830)
96. Giardiasis - First case in Russia (1859)
97. Toxoplasmosis - First case in Germany (1908)
98. Trichuriasis - First case in Germany (1761)
99. Ascariasis - First case in China (1935)
100. Hookworm Disease - First case in Italy (1838)
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